Dianabol 25

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Dianabol 25
Dianabol, known as the pioneering brand for the inaugural oral anabolic steroid, methandrostenolone, has maintained its prominent status in bodybuilding for four decades. It is widely regarded as the go-to steroid for those seeking to enhance muscle size and strength during bulking cycles.
Dianabol 25
Dianabol, known as the pioneering brand for the inaugural oral anabolic steroid, methandrostenolone, has maintained its prominent status in bodybuilding for four decades. It is widely regarded as the go-to steroid for those seeking to enhance muscle size and strength during bulking cycles.

Dianabol, also known as DBOL, is a well-known brand name for methandienone, which falls under the category of androgen steroids.

DBOL holds a special place among athletes, bodybuilders, and powerlifters due to its remarkable benefits and minimal drawbacks. Numerous advertisements have extolled the potency of this anabolic steroid.
Its popularity stems from its ability to rapidly enhance strength and muscle growth, delivering noticeable results within just a few weeks. Many athletes turn to Dianabol to improve their physique and performance. Remarkably, it is one of the most affordable steroids on the market, with a full regimen costing less than $100. Various social media ads showcase the power and advantages of this steroid.
However, it’s crucial to note that Dianabol can pose potential health risks when used without the guidance of a registered medical professional. Consequently, despite its popularity within the bodybuilding community, Dianabol is classified as a controlled substance (Schedule III) in both the United States and the United Kingdom.

It’s worth mentioning that, as per Wikipedia, Dianabol is legally obtainable without a prescription in certain countries like Mexico, and there are advertisements guiding individuals on where to purchase this steroid.


In 1955, researchers at the Chemische Industries Base (CIBA) laboratories in Basel, Switzerland, introduced Metandienone for the first time. Subsequently, CIBA launched this pharmaceutical product in the United States in 1958, marketing it under the name Dianobol.

Initially, physicians administered this medication to burn victims and the elderly to address conditions like hypogonadism, with dosages typically ranging from 5 to 10 mg/day in men and 2.5 mg/day in women. Additionally, it was prescribed for androgen deficiency.


This steroid is a straightforward, commonly utilized compound embraced by professional bodybuilders, athletes, and powerlifters in a particular setting. According to research findings, it’s available in oral tablet form and isn’t recommended for injection. Typically, it’s combined with other similar steroids to maximize its advantages.

This particular steroid is classified as an androgen receptor (AR) agonist, targeting biological receptors associated with androgens such as testosterone and dihydrotestosterone (DHT). It boasts potent anabolic properties with comparatively milder androgenic and estrogenic effects.

Bodybuilders aim for enhanced muscle definition, increased strength, and reduced body fat, while athletes seek improved stamina, endurance, and power. Consequently, incorporating Dianabol into a steroid cycle alongside others with complementary objectives is essential.
Brand Names
In addition to DIANABOL (also spelled DBOL), methandienone is marketed under a diverse range of brand names. Some of these include VETANABOL, REFORVIT-B, NAPOSIM, METANABOL, DRONABOL, CHINLIPAN, AVERBOL, and ANABOL, among others. These products are also available in various dosage forms, as illustrated in numerous advertisements.
Generic Names
Metandienone, also known as methandienone in British terminology, serves as the generic and International Non-proprietary Name (INN) for DBOL. In academic and scientific circles, it is often referred to as methandrostenolone and dehydro methyltestosterone, based on its chemical structure. It’s crucial to note that the former synonym, methandrostenolone, should not be confused with methenolone (primobolan), which is an entirely different Androgenic Anabolic Steroid (AAS).
John Bosley Ziegler

Not long thereafter, the off-label utilization of steroids as a performance enhancer among athletes, specifically in weight-lifting competitions, began to surface. This practice made its way to American university athletes through the efforts of Dr. John Bosley Ziegler, an American Olympic physician. This initiative was prompted in response to the unfair advantage gained by Russian professional athletes who were using injectable testosterone for rapid and extraordinary performance benefits.

Dr. John Bosley Ziegler, a native of Maryland, is credited with the introduction and development of steroids in the United States, with a particular focus on the anabolic steroid known as methandienone.
Based in Olney, Maryland, Dr. Ziegler specialized in treating handicapped and seriously injured patients while simultaneously conducting chemistry research for the Swiss pharmaceutical company CIBA.

Throughout his professional career, he dedicated himself to the study of steroids and eventually served as the official team doctor for American bodybuilder representatives in the Olympics, where he introduced them to the use of steroids.

Chemical Structure

Metandienone, also known as 17α-methyl-δ1-testosterone or 17α-methylandrost-1,4-dien-17β-ol-3-one, is a synthetic anabolic androstane steroid (AAS) and a 17α-alkylated derivative of testosterone. It is a modified form of testosterone, featuring a methyl group at the C17-alpha position and an additional covalent double bond between the C1 and C2 positions.

Furthermore, this drug is a 17α-methylated derivative of boldenone (δ1-testosterone) and a δ1 analogue of methyltestosterone (17α-methyltestosterone).

Dianabol (Methandienone) is categorized as an anabolic androgen, closely resembling the male hormone testosterone. It is primarily administered orally, as attempts to introduce it via injection have proven largely ineffective. Due to its structural characteristics, this anabolic steroid undergoes degradation in the body when injected, making it ideally suited for oral consumption.

Pharmacodynamics (What does the drug do to our body)

Methandienone, acting as an androgen analogue, interacts with and activates the androgen receptor (AR), leading to rapid increases in glycogenolysis, protein synthesis, and muscle strength within a short timeframe.

Although it can be metabolized by 5α-reductase into a more potent anabolic androgenic steroid (AAS) called methyl-1-testosterone (17α-methyl-δ1-DHT), it’s important to note that methandienone exhibits minimal affinity for this enzyme. Consequently, only trace amounts of methyl-1-testosterone are produced.

Therefore, it’s worth mentioning that 5α-reductase inhibitors such as finasteride and dutasteride will have little to no impact on reducing the androgenic effects of methandienone (DBOL).

Anabolic-Androgenic Activity Ratio

Although the anabolic-to-androgenic activity ratio of methandienone is improving compared to that of testosterone, it still retains androgenic properties and can lead to virilization in women and young individuals. Therefore, its usage is limited to men.

When exposed to the aromatase enzyme, methandienone can undergo aromatization, resulting in the conversion into the estrogen methyl estradiol (17α-methyl estradiol). However, this estrogen remains resistant to degradation, leading to estrogenic effects such as gynecomastia (male breast enlargement, colloquially known as “man boobs”) and fluid retention.
To mitigate or prevent these estrogenic side effects, the concurrent use of an anti-estrogen, such as an aromatase inhibitor like anastrozole or a selective estrogen receptor modulator like tamoxifen, can be effective.

It’s important to note that methandienone does not exhibit progestogenic activity. Like other 17α-alkylated anabolic androgenic steroids (AAS), methandienone can impose significant liver toxicity.

Pharmacokinetics (What does our body do to the drug)

Methandienone exhibits high oral bioavailability, with efficient absorption into the body. Notably, it demonstrates a significantly lower binding affinity to human serum Sex Hormone Binding Globulin (SHBG) compared to testosterone, around 10%, and even less, approximately 2%, compared to dihydrotestosterone (DHT).

The metabolism of this steroid takes place primarily within the liver and involves several processes, including 6β-hydroxylation, 3α- and 3β-oxidation, 5β-reduction, 17-epimerization, and conjugation, among other reactions.

In contrast to methyltestosterone, methandienone lacks a C1(2) covalent double bond, preventing the formation of 5α-reduced metabolites. Methandienone has an elimination half-life of approximately 5-6 hours and is excreted primarily through urine.


Hickson, Robert, and their team conducted research on young adult male rats, examining the impacts of anabolic steroid administration on body composition, organ weights, and high-intensity sprint running. They carried out separate and combined experiments for this purpose.

When administering Dianabol (methandrostenolone) at a dosage of 1 mg/day for 8 weeks, no significant changes in muscle weight or lean body mass were observed in either the sedentary or trained rats.

In contrast, the sprint training program yielded notable results. It led to reduced body weight and a lower percentage of body fat compared to sedentary rats (13.5% vs. 8.5%, respectively, p<0.01). Additionally, there was a significant increase in relative lean body mass among the rats in the sprint training group compared to sedentary rats (91.5% vs. 86.5%, p<0.01).

Based on these findings, researchers have determined that (a) young, healthy male animals with regular androgen levels already have sufficient stimulation for muscle growth, making additional anabolic steroid doses ineffective, and (b) the alterations in body composition resulting from short-duration, high-intensity sprint training closely resemble those achieved through endurance exercise training.
Dosage Form
Metandienone is supplied in oral tablet form, with dosages of 2.5mg and 5mg. Typically, it is prescribed at a daily dose of 5 to 10 mg for men and 2.5 mg for women as part of androgen replacement therapy to address hypogonadism. However, it’s important to note that its use has been discontinued and is prohibited in many countries, including the United States, rendering it illegal.
Dosage Range

In the realm of bodybuilding, the recommended dosages for these steroids typically range from 10mg to 50mg per day. It’s crucial to bear in mind that this particular steroid isn’t advisable for women due to its androgenic properties and potential side effects.

While many individuals can tolerate this steroid on an empty stomach, as a precaution, it is recommended to take it after a meal if you plan to include it in your cycle.

Prior to a workout session, some users opt to consume their entire daily quota of 50mg of metandienone for a short period in order to prime their bodies. This strategy is believed to maximize the benefits of the steroid, allowing it to perform at its peak effectiveness.

Administration Method

This steroid is commonly favored in bodybuilding competitions and powerlifting due to its relatively short half-life of 5-6 hours. To ensure a consistent presence of this steroid in your system, professionals typically recommend a twice-daily dosing regimen.

Furthermore, this dosing strategy maximizes the benefits of the steroid, as it prevents further concentration spikes in the system, which can occur during a cycle and lead to plateaus in effectiveness.


For newcomers, it’s generally recommended to avoid high doses of metandienone. Starting with a lower dosage, around 20mg to 25mg per day, is advisable during the initial phase of your cycle.

If you’re aiming for enhanced results, you can consider increasing your daily intake to 30mg to 35mg.

The choice of steroids to stack with Dianabol depends on your specific goals and the purpose of your usage. For instance, bodybuilders and athletes pursue distinct objectives, leading to varied combinations.

This steroid becomes detectable in the body within just three days of use. To ensure it goes undetected in tests, it is advisable to discontinue usage for a minimum of three months before undergoing testing.
Detection in Body Fluids

Methandienone undergoes significant hepatic transformation through various enzymatic pathways. Its primary urinary metabolite remains traceable for a duration of up to three days, while a newly identified hydroxymethyl end product can be detected in urine for as long as 19 days following a single 5 mg oral dose.

Due to the distinctive nature of some methandienone metabolites, detection methods in urine samples commonly rely on gas chromatography-mass spectrometry.

Quick Results

The full effects of this steroid typically manifest within five to seven days. Due to its rapid action, bodybuilders often employ it as the initial step in their muscle-building journey, whereas it may take longer for average individuals to notice results.

Similar to other steroids, it’s important to note that regardless of the dosage and effort invested, there will come a point where its impact levels off.

However, when this plateau is reached, Dianabol begins to demonstrate its true benefit: a slower yet efficient mode of operation that contributes to the preservation of muscle gains.

Advantages of Dianabol

Dianabol is a highly favored choice among bodybuilders during bulking seasons due to its remarkable benefits. Functioning as a steroid, it operates by rapidly saturating muscle tissue with water, a critical component of muscle development.
Upon oral administration of this steroid, users can swiftly experience an uptick in protein synthesis and a surge in nitrogen levels, which are pivotal for augmenting muscle size and strength.
Facilitates Muscle Mass Gain
Moreover, it thwarts the elevation of cortisol, a hormone notorious for breaking down muscle tissue, thus simplifying the process of gaining muscle mass. During its heyday in the 1950s, athletes would regularly ingest this steroid to achieve their mass-building objectives.
Yields Substantial Muscle Gains
Beyond its ability to deliver substantial muscle gains, Dianabol also excels at enhancing strength without compromising fat deposits. This steroid expedites glycogenolysis, the process of converting glycogen into glucose—a fundamental energy source for the body. This means that the carbohydrates you consume become exceptionally valuable for constructing more muscle.
Users who incorporate this steroid into their regimen have reported heightened levels of happiness, motivation, and confidence, thanks to the elevation of testosterone, the male hormone. Dianabol stands out as the ultimate choice for those seeking rapid muscle growth and increased strength.
Some of the most sought-after benefits of this steroid include:
  • Accelerated and safer muscle gains.
  • Remarkable boosts in strength and stamina.
  • Enhanced focus and motivation.
  • Expedited and superior results (often within a month).
  • No need for injections.
  • Speedier recovery periods.
  • Reduction in muscle fatigue.
DBOL as a Cycle Catalyst

DBOL is often employed as a catalyst to initiate cycles that involve other compounds with slower onset times. For instance, testosterone variants like Testosterone Enanthate or Testosterone Cypionate may not manifest their effects until approximately the second or third week of the cycle.
Enhancing Strength Through DBOL

In such scenarios, this anabolic steroid serves as a catalyst to maximize the benefits of the cycle. By the time testosterone starts exerting its effects, DBOL would have already produced notable strength enhancements.

Drug Interactions
When taking Dianabol in conjunction with other medications, it’s important to be aware of potential serious side effects resulting from drug interactions. To ensure your safety, engage in a comprehensive conversation with your healthcare provider about your medical history, past prescriptions, and any known allergies. Adhere closely to your doctor’s guidance at all times.
Consult Your Physician

Please refrain from initiating, discontinuing, or modifying the dosage of any medication in your regimen without first seeking guidance from your physician while undergoing your Dianabol cycle.

It is generally not recommended for women to use this steroid, as it carries the potential risk of inducing masculinizing effects.

Missed a Dose?

If you happen to forget a dose of your medication, promptly take it upon recollection. However, if you realize you missed a dose after a 24-hour interval has passed, it is advisable to forgo that particular dosage. Instead, proceed with your next scheduled dose after consulting your healthcare provider.

It is strongly recommended that you consult your doctor prior to taking your subsequent dose. Under no circumstances should you exceed your prescribed dosage unless expressly instructed to do so.

Potential Adverse Effects

As Dianobol is structurally similar to androgens, it can lead to unwanted outcomes resulting from the conversion of testosterone into estrogen (a female hormone), a process known as aromatization.
Among the most frequently reported side effects of this drug are:
  • Virilism: A condition characterized by the development of masculine traits in women.
  • Priapism: An extended and painful erection of the penis.
  • Facial acne.
  • Increased sexual desire.
Additionally, although rare, Dianobol may occasionally give rise to more serious side effects that are important to be aware of, even if they are not common. These include:
  • Elevated calcium levels in the blood.
  • Potential risk of liver and prostate gland cancer, often accompanied by an enlarged prostate.
  • Noticeable water retention.
  • Leg cramps.
  • Difficulty sleeping.
  • Nighttime chills.
  • Diarrhea and abdominal bloating.
  • Altered interest in sexual activity.
  • Excessive fat and bilirubin levels in the blood.
  • Increased risk of heart attack or heart failure.
  • Reduced sperm count.
  • Jaundice, indicated by yellowing of the eyes or skin.
  • Mood fluctuations, ranging from depression to excessive excitement.
  • Aggressive behavior.
  • Decreased testicle size.
  • Skin darkening.
  • Irritability.
The common side effects of this steroid stem from its inhibition of natural testosterone production. Users can address this issue by supplementing with exogenous testosterone, thereby maintaining healthy testosterone levels in the body.

To minimize side effects, it is crucial to adhere to the prescribed dosages of the drug and not exceed the recommended cycle duration of 6 weeks.

Legal Status

Following a 1962 amendment in the United States, the FDA initiated a review of the effectiveness and safety of drugs approved prior to 1962, including DIANABOL. In 1965, under FDA pressure, CIBA was compelled to conduct further investigations into its medical applications.
Strength Enhancement
Consequently, this steroid was granted renewed approval for the treatment of osteoporosis in menopausal women and dwarfism. Ongoing FDA pressures led to the withdrawal of this steroid from the U.S. market in 1983, resulting in the cessation of generic manufacturing. Its non-medical use as a strength enhancer and muscle builder was officially prohibited in the United States under the Anabolic Steroids Control Act of 1990.
While methandienone is subject to stringent regulation and is no longer included in the U.S. formulary, it continues to be manufactured and used for medical purposes in other countries such as Mexico and Asia. In the realm of sports, authorities have imposed strict limitations on its usage.
Recent Developments

Since its ban in the United States and other countries, methandienone has found its way into nutritional supplements like the “1-T matrix,” which can be acquired through telephone orders. Metandienone, available only through special prescriptions from licensed doctors, is not disclosed on product labels, and its concentrations vary from one capsule to another.

Usage and Dosage


Side Effects

2 reviews for Dianabol 25

  1. Sam

    Reliable source, trustworthy.

  2. Frank

    Credible and trustworthy supplier.

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